Vitamin D
Vitamin D
Vitamin D, Cholecalciferol, Ergocalciferol
Vitamin D is consumed in the form of vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). It can be obtained exogenously (via food) or by endogenous synthesis from cholesterol, which is initiated by sun’s UVB rays incidence on the skin. The main function of vitamin D is to maintain calcium homeostasis. Its deficiency can be observed in individuals who have low sun exposure, Lipid Absorption problems or dietary problems.
Supplement, Topical Use, Present in food
Origin
Plant Based, Animal Product, Synthetic
Source
Milk, Eggs, Meat, Fish, Synthetic, Cereals
Type
Vitamin
Bones and joints support the body and muscles, which make you move. They also take an important part in controlling vitamins, hormones and minerals, such as calcium, vitamin D and thyroid hormones. Supplements that affect bone and joint health help their structure and strength, in addition to contributing to the healthy balance of involved components.
Vitamin D in its active form regulates calcium and phosphorus metabolism, maintaining their serum levels in a normal state, providing conditions for most metabolic functions, including bone mineralization.. Vitamin D deficiency can cause growth retardation, bone abnormalities, and increased risk of fractures in adulthood.
Level of Evidence
High
Energy and mood are associated with several external and internal factors. Hormone release, brain chemical balance, nutrient metabolism, and several other elements alter the way the body and mind respond to daily activities. The compounds that benefit energy and mood are the ones that help in the balance of all these factors.
Researchers found that vitamin D deficiency is more common in those who experience anxiety and other mood disorders, therefore supplementing this vitamin might be a helpful treatment.
Level of Evidence
Low
Research has shown that vitamin D might play an important role in regulating mood and warding off depression. In some studies, scientists found that people with depression who received vitamin D supplements noticed an improvement in their symptoms.
Level of Evidence
Low
Hormones are chemical substances synthesized by the body to act as cellular signalers. Hormones’ main function is to work by regulating growth, development, reproduction and the functions of many tissues, as well as the metabolic processes of the organism. It is important to maintain good levels of all hormones, as any change can result in different kinds of dysfunction. Supplements that help regulate hormones work in different ways, which can increase their synthesis and secretion or even intervene in positive and negative feedbacks in the body.
Vitamin D active form functions as a steroid hormone in the body. There is a correlation between vitamin D deficiency and low testosterone. Increasing vitamin D stores may boost testosterone levels and improve other related sex hormone measures.
Level of Evidence
Medium
The immune system is made up of cells, tissues and organs that act in the organism’s defense against the harmful effects of external microorganisms. The supplements indicated for immunity act as strengthening agents of this system, increasing the antibodies production and, consequently, its defense activity.
In the immune system, vitamin D can perform various functions, such as regulating lymphocyte activation and increasing the number and function of regulatory T cells. Vitamin D can also prevent the development of autoimmune diseases and could be used to treat certain ones of them. The effect of vitamin D on the immune system is primary increased innate immunity (individual immunity) associated with acquired immunity regulation. Evidences suggest that vitamin D may play an important role in regulating the immune system and preventing immune-mediated diseases.
Level of Evidence
High
To live longer is necessary to live well, meaning that overall well-being, healthy organs, a healthy brain and good habits are taken into consideration when it comes to longevity. All of those circumstances require a healthy lifestyle, which works directly in the prevention of illnesses or conditions that might negatively influence your health. There are a lot nutraceutics and supplements that can help the body to stay safe and sound, just as it should be.
Vitamin D synthesis decreases with age as the body becomes less efficient in doing so with time. It is known that this vitamin plays a crucial role in lots of aspects of the body’s metabolism. Works mainly in hormone regulation and in bone health, which are two of the most impaired functions in seniors. Having a good Vitamin D level also helps the body to maintain homeostasis and circulation.
The concept of healthy nutrition involves a good functioning and homeostasis of all systems and organs of the body, in order to prevent diseases and dysfunctions. The substances consumed for this purpose help general health because they are essential nutrients that have wide functionality in many areas of the body, influencing inflammatory signaling and metabolic pathways that are strongly relevant to most major health problems.
Vitamin D is consumed in the form of vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). It can be obtained exogenously (via food) or by endogenous synthesis from cholesterol, which is initiated by sun’s UVB rays incidence on the skin. The main function of vitamin D is to maintain calcium homeostasis. Its deficiency can be observed in individuals who have low sun exposure, lipid absorption problems or dietary problems.
Age Range
Children (0-12), Teenagers (13-19), Adults (20-59), Seniors (60>)
Toxicity
May be toxic in high doses
Side effects
Sleepness, Constipation, High Blood Pressure, Psicological Effects, Mental Confusion
Warnings
There are no contraindications
Why be Careful
Vitamin D toxicity is very rare, but too exceded supplementation can result in hypervitaminosis D (excess vitamin D). This condition can increase calcium levels, which severely damages bones and kidneys over time.
Compound
Calcium
P/N
Positive
Compound Description
Vitamin D is the Hormone that regulates calcium and phosphorus metabolism. Its main purpose is to maintain the serum levels of these Minerals in a normal state, providing proper conditions for most metabolic functions, including bone mineralization. Studies show that normal serum vitamin D levels promote 30% of dietary calcium Absorption. Reduction in calcium and vitamin D intake can negatively influence bone development, leading to rickets (softening and weakening of bones).
Level of Evidence
Very High
Compound
Vitamin K
P/N
Positive
Compound Description
Vitamin D is potentially synergistic to vitamin K supplementation, as they share many mechanisms of action in cardiovascular systems and bone metabolism. Controlled studies have found that vitamin K, calcium and vitamin D supplementation increased carotid artery elasticity compared to vitamin K-free supplementation, but more evidence is needed to prove the role of vitamin K in cardiovascular disease reduced risk.
Level of Evidence
High
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