Lutein

Lutein, Lutein, zeaxanthin

Lutein is an important carotenoid, which is a yellow/red pigment found in fruits, vegetables, and egg yolks. A potent antioxidant that works mainly in eye health against free radicals in the retina and macula region. It also has an isomer (compound of identical chemical formula) called zeaxanthin, that works synergically in the eyes.

Nutraceutic

  • Origin Plant Based, Animal Product, Synthetic
  • Source Eggs, Leafy Greens, Corn, Paprika
  • Type Carotenoid

Eye Health

The eyes are very important organs for the quality of life in general. They are extremely sensitive, thus they deserve preventive care because when they are harmed, they are not easily treated. The compounds used for eye health are mainly specific antioxidants and fatty acids.
  • Eye Function

    The eyes are extremely sensitive, thus they deserve preventive care because when they are harmed, they are not easily treated. The compounds used for eye health are mainly specific antioxidants and fatty acids.
  • Age Range Adults (20-59), Seniors (>60)
  • Toxicity Not toxic
  • Side effects No adverse side effects reported untill now
  • Warnings Skin Cancer

Why be Careful

There is speculation that high levels of lutein in the blood may be associated with an increased risk of skin cancer in individuals with a predisposition or history of the disease.

References

  1. a b c d Goodrow EF, et al. Consumption of one egg per day increases serum lutein and zeaxanthin concentrations in older adults without altering serum lipid and lipoprotein cholesterol concentrationsJ Nutr. (2006)
  2. a b c d Handelman GJ, et al. Lutein and zeaxanthin concentrations in plasma after dietary supplementation with egg yolkAm J Clin Nutr. (1999)
  3. a b c d Wenzel AJ, et al. A 12-wk egg intervention increases serum zeaxanthin and macular pigment optical density in womenJ Nutr. (2006)
  4. a b c d e f g h Hammond BR Jr, et al. Dietary modification of human macular pigment densityInvest Ophthalmol Vis Sci. (1997)
  5. a b Solomons NW, Bulux J. Plant sources of vitamin A and human nutrition revisited: recent evidence from developing countriesNutr Rev. (1994)
  6. ^ Stahl W, Sies H. Uptake of lycopene and its geometrical isomers is greater from heat-processed than from unprocessed tomato juice in humansJ Nutr. (1992)
  7. a b c d e f g h i Chung HY, Rasmussen HM, Johnson EJ. Lutein bioavailability is higher from lutein-enriched eggs than from supplements and spinach in menJ Nutr. (2004)
  8. a b c d Vishwanathan R, et al. Consumption of 2 and 4 egg yolks/d for 5 wk increases macular pigment concentrations in older adults with low macular pigment taking cholesterol-lowering statinsAm J Clin Nutr. (2009)
  9. ^ Surai PF, et al. Designer egg evaluation in a controlled trialEur J Clin Nutr. (2000)
  10. a b Borel P, et al. Low and high responders to pharmacological doses of beta-carotene: proportion in the population, mechanisms involved and consequences on beta-carotene metabolismJ Lipid Res. (1998)
  11. ^ Johnson EJ, et al. Ingestion by men of a combined dose of beta-carotene and lycopene does not affect the absorption of beta-carotene but improves that of lycopeneJ Nutr. (1997)
  12. ^ Henderson CT, et al. Normal serum response to oral beta-carotene in humansJ Am Coll Nutr. (1989)
  13. ^ Ahmed SS, Lott MN, Marcus DM. The macular xanthophyllsSurv Ophthalmol. (2005)
  14. ^ Junghans A, Sies H, Stahl W. Macular pigments lutein and zeaxanthin as blue light filters studied in liposomesArch Biochem Biophys. (2001)
  15. ^ la Cour M, Kiilgaard JF, Nissen MH. Age-related macular degeneration: epidemiology and optimal treatmentDrugs Aging. (2002)
  16. ^ Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8Arch Ophthalmol. (2001)
  17. ^ van Leeuwen R, et al. Dietary intake of antioxidants and risk of age-related macular degenerationJAMA. (2005)
  18. ^ Snellen EL, et al. Neovascular age-related macular degeneration and its relationship to antioxidant intakeActa Ophthalmol Scand. (2002)
  19. ^ [No authors listed. Risk factors for neovascular age-related macular degeneration. The Eye Disease Case-Control Study GroupArch Ophthalmol. (1992)
  20. ^ Beatty S, et al. Macular pigment and risk for age-related macular degeneration in subjects from a Northern European populationInvest Ophthalmol Vis Sci. (2001)