Appetite include physical hunger, subjective appetite (desire to eat) and satiety. These aspects are controlled and regulated by hormones (leptin, ghrelin, serotonin, etc.) that act in the gastrointestinal tract and in the brain through negative feedback. In addition to hormones, appetite is also influenced by metabolic factors, hydration, blood glucose, intestinal motility, among others. The compounds that influence appetite are those that regulate the hormones involved, assist in satiety, benefit the gastrointestinal tract, improve blood glucose, among others.