Iron and Zinc can directly interfere with each other Absorption. The increase in dietary iron concentrations meddles negatively in Zinc bioavailability, while high intakes of Zinc results in lower serum ferritin. In the same way, Calcium-rich foods can decrease Zinc absorption, when consumed at the same time, thus high calcium diets might modify body’s requirement of zinc.

Retinol-binding protein (RBP) is responsible for eye health and Vitamin A transportation from the liver to other tissues, and it depends on zinc plasma concentrations to work properly. Zinc deficiency might complicate Vitamin A metabolism, therefore leading to night blindness (difficulty ou incapability to see in dark places)