NAC
NAC
N-Acetylcysteine
NAC is a supplement form of cysteine which is a amino acid the body produces itself. Its main role in the organism is to be a powerful coajuvant in antioxidant metabolism. NAC is the major Glutathione precursor, that is the most important antioxidant among cells, which helps neutralize free radicals that can damage tissues in the body.
Supplement
Origin
Synthetic
Source
Synthetic
Type
Amino Acid Precursor
Energy and mood are associated with several external and internal factors. Hormone release, brain chemical balance, nutrient metabolism, and several other elements alter the way the body and mind respond to daily activities. The compounds that benefit energy and mood are the ones that help in the balance of all these factors.
NAC helps regulate levels of glutamate (the most important neurotransmitter in the brain). While glutamate is required for normal brain action, excess glutamate paired with glutathione depletion can cause mood disorders. This may contribute to mental health conditions, such as bipolar disorder, schizophrenia, obsessive-compulsive disorder (OCD) and anxiety. For people with bipolar disease and depression, NAC may help decrease symptoms and improve your overall ability to function.
Level of Evidence
Medium
The immune system is made up of cells, tissues and organs that act in the organism’s defense against the harmful effects of external microorganisms. The supplements indicated for immunity act as strengthening agents of this system, increasing the antibodies production and, consequently, its defense activity.
NAC’s may reduce respiratory symptoms by acting as a mucolytic agent and reducing sputum formation. Its antioxidant and expectorant capacity can improve lung function by decreasing inflammation as well as breaking up mucus.
Level of Evidence
Low
The liver is responsible for many physiological processes, such as nutrient metabolism, filtration of toxins, lipid profile regulation, etc. It is an extremely important organ for the organism, since it acts in general body homeostasis. The substances that help in liver functioning aids the detoxification pathways, preventing the liver from overloading itself.
NAC is needed to synthesize glutathione. Glutathione is one of the body’s most important antioxidants, which helps neutralize free radicals that can damage cells and tissues. It’s essential for immune health and fighting cellular damage. NAC plays an important role in your body’s detoxification process. It can help prevent side effects of drugs and environmental toxins, also has applications for other liver diseases due to its antioxidant and anti-inflammatory benefits
Level of Evidence
Medium
Age Range
Adults (20-59), Seniors (60>)
Toxicity
May be toxic in high doses
Side effects
Nausea, Vomiting, Diarrhea, Constipation
Warnings
Bleeding Disorders, Blood Thinning Medications
Why be Careful
People with bleeding disorders or taking blood thinning medications should not take NAC, as it may slow blood clotting.
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