D-Aspartic Acid

D-Aspartic Acid, D-AA

D-Aspartic acid is a ##nonessential## ##amino acid##, which is a precursor of ##protein## molecules, oligopeptides, purines, nucleic acids, and others. It also acts as an excitatory neurotransmitter in the brain. D-Aspartic acid works in the central region of the brain that participates in sexual ##hormones## secretion, such as luteinizing hormone, follicle stimulating and especially testosterone.

Nutraceutic

  • Origin Animal Product, Synthetic, Nonessential
  • Source Milk, Eggs, Meat, Fish, Fruits, Vegetables, Eggplant, Peanuts, Walnuts, Brazil Nuts, Almonds, Coconut, Hazelnut, Bananas, Nonessential, Synthetic
  • Type Amino Acid
  • Age Range Adults (20-59)
  • Toxicity There is no evidence of toxicity until now
  • Side effects No adverse side effects reported untill now
  • Warnings Pregnancy

Why be Careful

D-aspartic acid is safe for healthy individuals, but individualized prescription is recommended. According to some studies, pregnant women should not consume this type of supplement, as it is possible that its consumption causes damage to the fetus brain.

References

  1. a b c d e f Man EH, Bada JL. Dietary D-amino acidsAnnu Rev Nutr. (1987)
  2. ^ Friedman M. Chemistry, nutrition, and microbiology of D-amino acidsJ Agric Food Chem. (1999)
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  11. a b D’Aniello A, et al. Occurrence of D-aspartic acid and N-methyl-D-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone releaseFASEB J. (2000)
  12. a b c Lee JA, et al. D-aspartate localization in the rat pituitary gland and retinaBrain Res. (1999)
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  17. a b D’Aniello A, et al. Involvement of D-aspartic acid in the synthesis of testosterone in rat testesLife Sci. (1996)
  18. ^ Sakai K, et al. Localization of D-aspartic acid in elongate spermatids in rat testisArch Biochem Biophys. (1998)
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  20. a b Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis.
  21. a b Pampillo M, et al. The effect of D-aspartate on luteinizing hormone-releasing hormone, alpha-melanocyte-stimulating hormone, GABA and dopamine releaseNeuroreport. (2002)
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  32. a b c d e f d-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men.
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