Lactobacillus reuteri, Lactobacillus casei, Probiotics, Lactobacilus
Lactobacillus are a variety of gram-positive and anaerobic bacteria found in the gut. Lactobacillus casei can be found in the intestinal microbiota, while lactobacillus reuteri is used as a probiotic supplement. They can perform various functions in the body, such as aiding digestion, improving the immune response, increasing the absorption of lactose by the body, among others.
- Origin: Bacteria
- Source: Itself, Yorgurt, Kefir, Miso, Tempeh, Cheese, Sauerkraut
- Type: Probiotic
- Age Range: Adults (18-60), Seniors (>60)
- Toxicity: May be toxic in high doses
- Outcomes: Immunity, Nutrient Issues
What are Lactobacilus benefits?
Table of relations
Published articles about Lactobacilus and Nutrient Issues
Cholesterol-lowering Effects Of Soluble-fiber Cereals As Part Of A Prudent Diet For Patients With Mild To Moderate Hypercholesterolemia
Supplementation of 10g psyllium husk via cereal in persons with high cholesterol for 6 weeks failed to influence hematological parameters and body weight while reducing total cholesterol and LDL-C.
Vitamin E Supplementation And In Vivo Immune Response In Healthy Elderly Subjects. A Randomized Controlled Trial
In otherwise healthy older adults given vitamin E supplementation at three doses (60, 200, and 800mg) for approximately eight months who received vaccinations, it appeared that while vitamin E did not influence the overall count of B and T cells that it increased the antibody response to hepatitis B and tetanus (but not diptheria) and immunity as assessed by DTH reactivity; the effect was most effective at 200mg (65% increase in DTH reactivity) with some but lesser effects seen at both 60mg (41%) and 800mg (49%) relative to placebo (17%).
Effect Of 50- And 100-mg Vitamin E Supplements On Cellular Immune Function In Noninstitutionalized Elderly Persons
Supplementation of 50mg and 100mg of vitamin E (as alpha-tocopherol) daily for six months in the elderly was able to significantly increase immunosupportive levels of IL-2 while decreasing IFN-gamma concentrations; the decrease in IL-4 concentrations failed to reach statistical significance. Alongside these changes was an increase in DTH responsiveness, indicative of increased immune responsiveness (and immunity). This response was markedly more pronounced in persons with lower DTH responsiveness at baseline.
Assessment Of The Safety Of High-dose, Short-term Supplementation With Vitamin E In Healthy Older Adults
Supplementation of 800mg of alpha-tocopherol daily for 30 days in otherwise healthy older persons (60+) noted that there was an increase in indices of T-cell mediated immunity but no other parameter was significantly affected by supplementation relative to placebo.
Safety And Tolerability Of Lactobacillus Reuteri DSM 17938 And Effects On Biomarkers In Healthy Adults: Results From A Randomized Masked Trial
In otherwise healthy adults given _l. reuteri_ DSM 17938 at 5x10^8^ CFU daily for two months was not associated with any severe side-effects and was well tolerated. Increases in fecal _l. reuteri_ were minimal in this study and not significantly different than placebo, and immune parameters (lymphocytes, monocytes, dendritic cells) were unaffected.
The Influence Of Probiotic Supplementation On Gut Permeability In Patients With Metabolic Syndrome: An Open Label, Randomized Pilot Study
YAKULT Light (65mL of a drink containing 10^8^ colonies per mL) daily for 3 months in persons with metabolic syndrome failed to modify neutrophil function or standard biomarkers while it increased bilirubin (to 0.73±0.18 mg/dl, still within the normal range), C-RP (1.86±2.48 mg/dl) with no effect on ALT (liver enzyme) or intestinal permeability, which was the main study parameter.
Effect Of A Probiotics Supplementation On Respiratory Infections And Immune And Hormonal Parameters During Intense Military Training
Male military cadets undergoing intense training were supplemented with L. casei or placebo. No significant effects were observed for respiratory tract infection symptoms or any immunological parameters. However, probiotic supplementation trended toward blunting rises in leukocyte, neutrophil, and CD19+ and also blunting a decline in salivary IgA all attributed to the intense training.
Low Fermentable Oligosaccharides, Disaccharides, Monosaccharides, And Polyols Diet Compared With Traditional Dietary Advice For Diarrhea-predominant Irritable Bowel Syndrome: A Parallel-group, Randomized Controlled Trial With Analysis Of Clinical And Microbiological Factors Associated With Patient Outcomes
In this randomized, parallel-group controlled trial, 108 patients with IBS-D were assigned to a 3-week low-FODMAP diet or traditional dietary advice based on modified National Institute for Clinical Excellence guidelines. Fecal samples were collected before and after the intervention for the analysis of short chain fatty acids and fecal microbiota. The primary endpoint was a ≥50 point reduction in the IBS Severity Scoring System. Intention-to-treat analysis indicated the primary endpoint was met in 55.6% of the patients in the low-FODMAP group and 48.1% in the traditional dietary advice group. During the first week, patients in the low-FODMAP group experienced greater reductions in defecation and excessive flatulence compared to the traditional dietary advice group, but these differences were absent thereafter. After the first week, abdominal pain and urgency also improved in the low-FODMAP group, but stool consistency did not improve in this group. The traditional dietary advice group did experience improvements in abdominal pain, stool consistency, excessive flatulence, and urgency. The low-FODMAP diet reduced carbohydrate-fermenting bacteria and associated saccharolytic fermentation activity. These changes were associated with symptom improvement in responders, and high baseline levels of saccharolytic activity were associated with greater symptom burden. Alpha-diversity based on the Shannon index was higher after the low-FODMAP diet, and concentrations of certain short-chain fatty acids were both elevated and reduced.
β-Galactooligosaccharide In Conjunction With Low FODMAP Diet Improves Irritable Bowel Syndrome Symptoms But Reduces Fecal Bifidobacteria
In this randomized, 3-arm controlled trial, 69 patients with IBS were assigned to a sham diet with placebo supplement (control), low-FODMAP diet with placebo (LFD), or a low-FODMAP diet plus 1.4g/day beta-galactooligosaccharide (a prebiotic) (LFD/B-GOS) for 4 weeks. Gastrointestinal symptoms, fecal microbiota, short-chain fatty acids, and urine metabolites were anaylzed. The low-FODMAP diet reduced Actinobacteria and butyrate. Though the addition of B-GOS to LFD produced greater improvements compared to the control group, B-GOS did not prevent the LFD-associated reduction in Bifidobacterium and did not produce greater results than LFD alone.
A Diet Low In FODMAPs Reduces Symptoms In Patients With Irritable Bowel Syndrome And A Probiotic Restores Bifidobacterium Species: A Randomized Controlled Trial
In this randomized, placebo-controlled study, 104 patients with IBS were assigned to a low-FODMAP or sham diet for 4 weeks in addition to taking a placebo or a multi-strain probiotic containing Streptococcus thermophilus DSM 24731, Bifidobacterium breve DSM 24732, B. longum DSM 24736, B. infantis DSM 24737, Lactobacillus acidophilus DSM 24735, L. plantarum DSM 24730, L. paracasei DSM 24733, L. delbrueckii subsp. bulgaricus DSM 24734. Incidence and severity of gastrointestinal symptoms, stool frequency, and stool consistency were measured daily for one week before the trial. Global and individual symptoms, general health, and quality of life data, and fecal samples were collected at baseline and after the intervention. The primary endpoints were symptom relief and Bifidobacterium species abundance. In the intention-to-treat analysis, a higher proportion of patients in the low FODMAP diet experienced adequate symptom relief, but the difference was not statistically significant. However, in the per protocol analysis, more patients on the low FODMAP diet had adequate symptom relief. IBS-SSS was significantly lower for patients on the low FODMAP diet compared with the sham diet, but results did not differ between the probiotic and placebo supplement. Quality of life did not change or differ between groups. Bifidobacterium abundance was lower in fecal samples from patients on the low FODMAP diet compared with the sham diet, and higher in samples from the probiotic group compared with placebo. Alpha- and beta-diversity did not differ.
Effects Of Low FODMAP Diet On Symptoms, Fecal Microbiome, And Markers Of Inflammation In Patients With Quiescent Inflammatory Bowel Disease In A Randomized Trial
In this randomized controlled trial, 52 patients with Crohn’s disease or ulcerative colitis were assigned to a low-FODMAP or control diet with dietary advice for 4 weeks. Gut symptoms, health-related quality of life (QoL), fecal microbiome composition and function, and T-cell phenotypes were analyzed at baseline and after 4 weeks. A greater proportion of patients reported adequate symptom relief on the low-FODMAP diet compared to the control diet. The reduction in IBS symptom severity score was not significantly different between the groups, but the low-FODMAP group reported lower scores for bloating and flatulence. Patients following the low-FODMAP diet reported higher QoL scores. Abundances of specific species were lower in the low-FODMAP group at the end of the study period, but relative abundance of the Bifidobacterium genus, microbiome diversity and inflammatory markers did not differ between groups. Fecal concentrations of total SCFA were lower following the low-FODMAP diet compared with the control diet. Absolute numbers or proportions of T-cell phenotypes did not differ between diets at the end of the trial.
A Low FODMAP Diet Is Associated With Changes In The Microbiota And Reduction In Breath Hydrogen But Not Colonic Volume In Healthy Subjects
In this randomized controlled parallel-design study, 37 healthy adults were assigned to a low-FODMAP diet with either maltodextrin (MD) or oligofructose (OF) (7g/day) for one week. At baseline and at the end of the trial, MRI was used to assess colonic volume, stool was collected for microbiota and metabolite analysis, and fasted hydrogen and methane breath testing were performed. In the low-FODMAP+MD, FODMAP intake was reduced from baseline and significantly lower than the low-FODMAP+OF diet (p<0.05). It did not differ from baseline during the low-FODMAP+OF diet. Carbohydrate intake was reduced during both low-FODMAP diets (p<0.05). Colonic volume increased significantly in both low-FODMAP groups, with no significant difference between the groups. Total microbial load was reduced after both dietary interventions. There was a a significant difference in microbial profile after the intervention, with the intervention accounting for 7% of the microbial variation. The low-FODMAP diet was associated with a reduction in the Actinobacteria phylum, which was partly driven by a non-significant decrease in the Bifidobacterium genus. Oligofructose supplementation reversed this effect, and both Actinobacteria and Bifidobacterium increased, though only the change in Actinobacteria was significant. Breath hydrogen increased in the OF group and decreased in the MD group from baseline. Lower breath methane correlated with lower microbial diversity, and higher breath hydrogen was associated with higher concentrations of stool butyrate. Breath gas production and Actinobacteria were both positively correlated with colonic volume at both time points, whereas the Firmicutes phyla was negatively correlated with colonic volume. There were no significant changes in fecal SCFA or breath methane production.
8.8-15g of psyllium husk daily was associated with an increase in fecal weight and moisture attributed to the gel forming fragment of psyllium husk.
Comparison Of The Effects Of Psyllium And Wheat Bran On Gastrointestinal Transit Time And Stool Characteristics
Relative to control, psyllium husk was associated with an increase in transit time as well as parameters of fecal weight; the other group, wheat bran, only increased intestinal motility.
Relative to baseline, psyllium fiber was able to increase water content and fecal weight in humans following oral consumption; this study noted comparable efficacy with a cellulose/pectin combination
25g of psyllium daily for 3 weeks was able to increase fecal weight, although with variability between subjects.
5g psyllium taken thrice a day for 6 weeks was able to significantly reduce glucose and all improve all parameters of a lipid panel in diabetic persons relative to placebo; treatment was well tolerated.
Influence Of Sibutramine, Orlistat And Ispaghula In Reducing Body Weight And Total Body Fat Content In Obese Individuals
two tablespoons thrice daily' of psyllium in obese persons for 150 days was associated with 5% weight loss; no placebo or unblinded control group was present, and psyllium underperformed relative to orlistat and sibutramine
Psyllium Supplementation In Adolescents Improves Fat Distribution & Lipid Profile: A Randomized, Participant-blinded, Placebo-controlled, Crossover Trial
In obese teenage males given either 6g of psyllium supplementation daily or placebo, supplementation was associated with a reduction in LDL-C and improvement in fat deposition (less breast fat) although most cardiovascular parameters were unchanged.
The absorption and different uses for each nutrient is highly linked to the body's immune system, which is the set of chemical reactions that protect us from any ''intruder'' and susteins our vital functions. All the vitamins and minerals are essencial for the whole functioning of this system.
Table of negative interactions
Related videos about Lactobacilus
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- ^ Kobayashi T1, et al. Oral administration of probiotic bacteria, Lactobacillus casei and Bifidobacterium breve, does not exacerbate neurological symptoms in experimental autoimmune encephalomyelitis. Immunopharmacol Immunotoxicol. (2010)
- ^ a b c d e Kobayashi T1, et al. Probiotic upregulation of peripheral IL-17 responses does not exacerbate neurological symptoms in experimental autoimmune encephalomyelitis mouse models. Immunopharmacol Immunotoxicol. (2012)
- ^ Afzali B1, et al. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol. (2007)
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