Fatigue Prevention
Muscle Health

Fatigue Prevention

Fatigue is characterized by a reduction in physical energy. It can also appear as acute and/or chronic fatigue. Acute fatigue is due to excessive activities, such as physical exercise. Chronic fatigue is multifactorial, influenced by metabolic disorders, nutrient deficiency, physical inactivity, causing tiredness and constant lack of motivation.The substances that help with that are neuroprotective, affecting metabolism, hormones and motor function.

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Consistent effects
Strength of effects
Scientific articles
A decrease in fatigue (mental fatigue when measured after the workout) results when BCAA supplementation is taken during exercise at a dose above 10g approximately.
Somewhat effective at reducing fatigue and, secondary thereto, at improving time to exhaustion.
The decrease in fatigue during exercise is assumed to underlie most of the benefit seen with training capacity (work volume), although in men who self-report fatigue issues supplemental citrulline appears to assist thereupon also (independent of exercise).
400 mg/kg/day in children and adolescents subject to traumatic brain injury reduces fatigue frequency from around 90% right down to near 10%. Fatigue is additionally reduced, though to a lesser degree, in cases of sleep deprivation.
The decrease in fatigue appears to be fairly strong and quite reliable when a coffee dose is given over a protracted period of your time or a high dose is given acutely; there are studies that have found a rise in fatigue, and one that found that it trusted the tactic of measuring fatigue, so it's possible that results, while generally positive, are going to be variable.
No studies found